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Andrographis paniculata -
A Potential Cure For The Global Panic
For thousands of years, herbs have been used in treating infectious and non-infectious diseases. Among them are Andrographis paniculata commonly known as ‘King of Bitters’ or Hempedu Bumi by our local community. This herb has been well researched for its potency as an immune booster, anti-inflammatory and antiviral effect. In previous experimental studies, Andrographis paniculata was found to be effective against viral infections such as dengue (Edwin et al., 2016), swine flu (Seniya et al.,2014), hepatitis C (Lee et al., 2014), chikungunya (Wintachai et al., 2015), influenza (Chen et al., 2009), Epstein-Barr virus (Lin et al., 2008) and herpes simplex virus 1 (Wiart et al., 2005). Due to its antiviral properties, Andrographis paniculata was chosen by many researchers to study its potency against the SARS-CoV-2 virus. In 2020, several studies have found a strong interaction through computational investigation of Andrographis paniculata on the suppression of SARS-CoV-2 virus.
The outbreak of COVID-19 caused by SARS-CoV-2 virus (a type of coronavirus) has infected about 91 million and brought close to two million deaths worldwide according to the Ministry of Health Malaysia as of today. It is difficult to discover medicinal drugs with all clinical trials and determine the adverse effects or side effects in this emerging situation. Due to the urgent global health crisis and rapid human to human transmission of Covid-19, some countries are in need to find a cost-effective potent drug which can be immediately used by ruling-out the time-consuming approach of drug development
In Thailand, Andrographis paniculata is included in the national list of essential medicines for primary health care. It became popular during the COVID-19 pandemic. In September 2020, Andrographis paniculata was being recommended by the Department of Thai Traditional and Alternative Medicine (DTAM) as the treatment for flu-like symptoms, fever, cough, sore throat, fatigue and muscle pain that was caused by the virus.
The Director-General of DTAM, Dr Marut Jirasetasiri said the preliminary trials showed that Andrographis paniculata could be effective in preventing Covid-19 virus intrusion into human cells. Both the cough volume and the symptoms severity of the patients decreased significantly within three days in the preliminary trials. Due to more evidence being needed to support its efficacy in humans, the trial of this plant extract entered the Phase 2 trial in September 2020.
According to a report by Bloomberg recently, Thailand's Health Ministry claimed that Andrographis paniculata, also known as Hempedu Bumi locally, has been proven to be effective as an alternative treatment to reduce the severity of COVID-19. Studies have shown that the plant extract can curb the virus and reduce the severity of the inflammation. Human clinical trials also showed that the patients' conditions improved within three days of treatment and without any side effects. This herb should be taken within 72 hours after the infection is confirmed positive.
While waiting for the vaccine to arrive, Thailand's Health Ministry has approved the use of this herbal extract in the treatment of early stages of the disease. This will be a cost effective alternative in the treatment of early symptoms of COVID-19 and at the same time providing relief to the patients. The herbal extract will be available in five government hospitals and will be expanded to other hospitals as well.
Kordel’s Cold Away with Folium Andrographis paniculata extract (AP-Bio™) is a fast-acting natural remedy that is clinically proven to manage all the symptoms of the common cold.
The symptoms of common cold include: -
COLD AWAY with AP-Bio™ - A Natural Solution
Most of the commonly used cold remedies target only 1 or 2 symptoms whereas AP-Bio™ is known to support the management of multiple symptoms of common cold providing faster relief. Not only does AP-Bio™ reduce the severity of the common cold, it can also prevent the onset of a cold in healthy individuals. So, when you feel you are going to be down with a cold or flu, go for AP-Bio™ immediately! Kill the virus before it gets worse. Act fast, suffer less.
Theracurmin® - The Preventive Remedy Against Virus Infection
A study published in October 2020 has concluded that consuming turmeric in our daily diet may be a useful preventive remedy against coronavirus. In this silico studies, scientists have found the constituent from turmeric like curcumin is significantly active against COVID-19 by inhibiting the virus main protease enzyme with remedial possibilities (Rajagopal et al., 2020).
Curcumin is the major constituent of the spice turmeric. Despite being proven to have many health benefits by extensive studies over the years, the main problem of normal curcumin is its poor bioavailability even in high doses (Poor absorption by body after ingestion).
Thanks to a new technology and innovation, the absorption problem of curcumin is in the past, giving mankind a promise of good health from the good old turmeric. Theravalues Corporation, a Japanese company, has developed an innovative curcumin
formulation called Theracurmin® that enhances the absorption of curcumin by 2700%. Theracurmin® is made from ultra-fine granulation and suspension technology, converting turmeric powder into sub-micron particles called nano-molecular curcumin. It can be rapidly absorbed within 1 hour and retained as long as 24 hours in the body, allowing the body to obtain fast and longer protection